Edward and Alphonse Elric are two alchemic brothers living in the rural town of Resembool. When they were young, their father had left them leaving only their mother to take care of them. Years later, their mother, Trisha Elric, died of a terminal illness and the two boys were so sicken with grief, the committed the greatest taboo in alachemy - Human Transmutation. However, this attempt failed, ultimately resulting in the loss of Edward's left leg and Alphonse's entire body. In a desperate effort to save his brother, Edward sacrificed his right arm to affix his brother's soul to a suit of armor. A State Alchemist by the name of Roy Mustang approaches the two boys one day and and he tells Edward to become a member of the State Military of the country to find a way to recover their bodies. After that, Edward's left leg and right arm are fitted with two sets of automail, a type of advanced prosthetic limb, created for him by his close family friends Winry Rockbell and her grandmother Pinako and leaves Resembool with Alphonse to become a State Alchemist.